The main motivation of the proposed research comes from the need to improve patient recovery and patient outcomes after complex reconstructive surgeries. The ability to monitor blood flow close to the surgical sutures is a critical issue during the first time after medical procedures. The research project herein presented will aim to design an implantable blood flow pressure sensor, made entirely of a self-powered, wearable and multifunctional flexible device, able to work as both detection and power supply-unit. Precise and wide-range pressure detection (from ultra-low (<1 kPa), to low (1–10 kPa), medium (10–100 kPa) and high (>100 kPa)) is the main aim of the project. Within this context, the postdoctoral researcher will focus on the exploration of new materials developed at the two groups (alone or combining them) to create piezoelectric and/or triboelectric pressure sensors by two approaches. The first is related to the utilization of mechanical energy to generate electricity, suitable for dynamic pressure monitoring, and the second to the transformation of chemical energy into electricity, for both static and dynamic pressure monitoring. The candidate will work in the physical and chemical synthesis of highly flexible van der Waals materials including 2D chalcogenides (Mo(S,Se)2, W(S,Se)2), and novel Q1-D chalcogenides and chalcohalides (Sb2(S,Se)3, (Sb,Bi)(S,Se)(I,Br)). This will include strategies for the management of these materials at nano and micro scale level, and the tuning of their physical and chemical properties (bandgap, absorption coefficient, conductivity, transport charge properties). These devices will be modified with biocompatible and biodegradable 3D-printed hydrogels (based on gelatine, alginate...) with complex architecture, for an accurate and precise control of both static and dynamic pressure. In addition, advanced materials and devices characterization will be performed.